A case diagnosed with Spitz nevus Pigmented Spitz nevus.

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A case of pigmented Spitz nevus in a 12-year-old boy is reported. Approximately 3 years previously he noticed a small pigmentation on the right dorsum pedis, andgradually increased in size and elevated.Physical examination revealed a 13×10mm, dome-shaped, black nodule with irregular margin.An excisional biopsy specimen was histologically diagnosed as nodular malignant melanoma at that time. A wide excision with skin grafting and right inguinal lymph node dissection were performed.Recently, we checked clinically and histologically again and requested a fluorescence microscopy of formalin-fixed paraffin-embedded unstained specimen and a DNA distribution histogram.We put the various reports together and finally made the established diagnosis aspigmented Spitz nevus.Occasionally, a differentiation of a pigmented Spitz nevus from a malignant melanoma is very difficult.So, we need more information such as a fluorescent finding and a distribution histogram to avoid a misdiagnosis.
日本皮膚悪性腫瘍学会の論文