Increased levels of beta 2-microglobulin in peripheral blood mononuclear cells and hepatocytes in patients with chronic hepatitis type B.

スポンサーリンク

概要

• 論文の詳細を見る

• The levels of beta 2-microglobulin (β2m) in peripheral blood mononuclear cells (PBMC) and livers from patients with chronic liver diseases type B were measured. β2m of liver and PBMC in chronic active hepatitis was higher than those of controls (p<0.01, p<0.01). β2m of PBMC are directly proportional to those of livers (r=0.746), β2m levels of PBMC in patients with chronic active hepatitis during the exacerbation of hepatitis was higher than those of remission of hepatitis. The levels of β2m in PBMC in vivo, was significantly increased during either inteferon α or β administration. Interferon-γ positive cells in the liver were exacted in the β2m increased group of chronic hepatitis type B. INF-γ production in the lymphocyte of livers, may play an important role in the occurence of liver injury in patients with chronic hepatitis type B.

• 財団法人 日本消化器病学会の論文

著者

• 宮岡 弘明

  愛媛大学医学部第3内科

関連論文

• Beta-2-microglobulin of peripheral blood mononuclear cells from patients with chronic HBV infection.
• Increased levels of beta 2-microglobulin in peripheral blood mononuclear cells and hepatocytes in patients with chronic hepatitis type B.
• Histochemical visualization of carbohydrate antigen 19-9 (CA19-9) in pancreas from patients with pancreatic cancer by using a monoclonal antibody.

スポンサーリンク