Immunohistological study for the ras oncogene products in colorectal cancer.

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概要

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• By using anti-NKH-ras and K-ras monoclonal antibodies, paraffin-embeded tissue specimens of 70 cases of colorectal cancers were immunohistologically examined. Correlation between incidence of expression of these oncogens and either of postoperative survival rate and stage of colorectal cancer were calculated.The positive rate of anti-NHK-ras and K-ras staining were correlated with maximum diameters of tumor, staging, degree of Dukes classification and depth of invasion. Positive and negative rates of between NHK-ras and K-ras staining were well coincident. The cumulative postoperative survival rate of negative casesfor anti-K-ras staining showed a significantly higher survival rate than that of the positive cases.

• 財団法人 日本消化器病学会の論文

著者

• 中郷 俊五

  長崎大学医学部外科学第2教室

関連論文

• Immunohistological study for the ras oncogene products in colorectal cancer.

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