Studies on albumin synthesis in the partially hepatectomized or carbontetrachloride-injured rat liver, by using 15N.

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概要

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• The effects of partial hepatectomy or carbontetrachloride hepatic injury on 15N incorporation into plasma albumin were studied in the rat, 3 hours after intraperitoneal injection of 15N-glycine. Under 40% hepatectomy, the 15N incorporation rate did not change. But over 40% hepatectomy, it decreased in proportion to the remained liver cell mass.Carbontetrachloride was injected twice a week for 8 weeks. The lowest 15N incorporation rate was seen at 2 weeks. It reached the highest level at 4 weeks and decreased gradually thereafter.These results were well in accordance with histological changes and with the alterations of DNA and RNA contents and RNA/DNA ratio of the liver.

• 財団法人 日本消化器病学会の論文

著者

• 水谷 正之

  東邦大学医学部第2内科学教室

関連論文

• Studies on albumin synthesis in the partially hepatectomized or carbontetrachloride-injured rat liver, by using 15N.

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