Diagnosis and clinical features of portal vein tumor thrombosis in hepatocellular carcinoma.
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Imaging diagnosis by ultrasound (US), X-ray computed tomography and angiography, and clinical findings of portal vein tumor thrombosis (PVTT) in hepatocellular carcinoma (HCC) were studied with respect to location of PVTT in 116 patients. PVTT were followed up by ultrasound in 11 of them and the changes of clinical findings were also studied.US showed the highest detection rate for PVTT compared with other imaging modalities. Patients with PVTT in the portal trunk had more severe liver dysfunction, and worse prognosis, and more advanced esophageal varices than the ones with PVTT in the peripheral branches of the portal vein. Extention of PVTT was classified into three types from the mode and speed of growth. PVTT with a rapid growth showed poor prognosis. It was also classified into four patterns with regard to the relationship between the initiation of PVTT and its extent from the main tumor. There were cases in which PVTT was produced during a stage when the main tumor was still small.It was shown that PVTT was closely interrelated with clinical findings and prognosis of HCC, and that diagnosis and therapy of PVTT are clinically important.
- 財団法人 日本消化器病学会の論文
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- Diagnosis and clinical features of portal vein tumor thrombosis in hepatocellular carcinoma.