Studies on gastric emptying time in patients with liver cirrhosis by radioisotope technique.

概要

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In order to elucidate the change of gastric emptying in liver cirrhosis, an examination was attempted to measure the half gastric emptying time (T1/2) employing 99mTc-DTPA. The study was performed by analyzing the gastroscintigram and the gastric emptying curve using the nuclear medicine data analyzer (shimazu Scinti Pack 1200).As aresult, a distinctive delay in half T1/2 was recognized in patients with liver cirrhosis, in comparison with the normal subjects. In addition, the delay in T1/2 is more remarkable in cirrhotic patients with esophageal varices and/or gastric varices.Furthermore, cirrhotic patients with erosive gastritis and/or gastric ulcer showed a more distinctive delay than in ones without gastric lesions. In cases in which the T1/2 emptying time exceeds 80 minutes, incidence of gastric lesions was high (80%).From the above observation, the delay in gastric emptying is considered as one of the factors contributing to the high incidence of gastric lesions in liver cirrhosis patients.
財団法人日本消化器病学会の論文