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The experimental acute pancreatitis was treated by various intravenous alimentation and the results were following;1) In the group of low calorie insusion (LCI), control of serum glucose was difficult; NEFA increased remarkably, GOT increased, and the level of serum protein decreased. But in the group of intravenous hyperalimentation with fat emulsion (IVHF), control of serum glucose was easy, NEFA did not increase, the level of phospholipid and serum protein increased. So, IVHF therapy was very effective.2) In the group of LCI, serum gastrin secretion and trypsin activity were not inhibited, but in the group of IVHF they were inhibited. In the group of LCI with trasylol, the activity of serum trypsin was not inhibited.3) Direct IVHF infusion to the pancreatic artery was carried out safely and without difficulty. Serum glucose and insulin level was well controlled, and gastrin secretion was inhibited.Thus we conclude that IVHF is very effective treatment for experimental acute pancreatitis, and presume that clinicaly IVHF is useful for acute pancreatitis especially in the severe cases.
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