STUDIES ON GASTRIC ACID AND PEPSIN SECRETION IN LIVER CIRRHOSIS
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概要
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Studies on gastric acid and pepsin secretion, fasting serum gastrin and secretin concentration had been carried out in 30 patients with liver cirrhosis. Higher levels of gastric acid and pepsin output, increment of gastric acid output and tetragastrin-stimulated volume rate were ob erved in liver cirrhosis with gastric ulcer than in those without gastric ulcer.Significantly higher ratio of gastric acid output to pepsin output was also obtained in liver cirrhosis, especially in those with gastric ulcer, than in gastric ulcer without liver disease. In conclusion it was suggested that gastric acid and pepsin might play an important role in gastric ulcer formation in liver cirrhosis, and that the manner of gastric secretion and mechanism of ulcer formation in gastric ulcer without liver disease might be different from those of liver cirrhosis with gastric ulcer.
- 財団法人 日本消化器病学会の論文