TEST MEAL COMBINED PANCREATIC FUNCTIONAL DIAGNOSTANT (PFD):An Attempt to Improve Diagnostic Value of PFD

概要

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A Test Meal combined PFD (TMC-PFD) using Sustagen was compared with the conventional PFD to improve the diagnostic value of PFD.Urinary excretion of PABA was significantly decreased (p<0.02) in 70% pancreatectomized rats in comparison with that of normal control rats by TMC-PFD, although no difference was noted between them by the conventional PFD.PABA excretion showed abnormal range in 90% pancreatectomized rats, while the excretion revealed normal one by PFD in 70% pancreatectomized rats in which PABA excretion was abnormal by TMC-PFD.In clinical cases of chronic pancreatitis which had disturbance of two factors in P-S test, PABA excretion by TMC-PFD was abnormal, although the excretion was normal by the conventional PFD.Those data, therefore, indicate that the Test Meal combined PFD is more useful than the conventional one as a screening test for exocrine pancreatic insufficiency.
財団法人日本消化器病学会の論文