鉤虫の感染様式に関する研究 : 特にアメリカ鉤虫感染期仔虫による口腔粘膜からの感染実験について

概要

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The author wanted to confirm whether or not Necator americanus is communicated through oral membranes and, should this be the case, whether the infection is influenced by the time length of contact with oral membranes. Experiments were conducted to observe whether a larvae can become Necator americanus in the human body by contact with oral membranes. The following results were obtained:I 1st experiment to apply larvae to oral membranes for 300 seconds.1) Infection was observed in four out of five volunteers.2) The four volunteers were free of apparent subjective symptoms in the time period up to expelling.3) As to objective symptoms, eosinophilie increased in the blood picture of the four volunteers infected.4) For the four volunteers infected, ova and larvae were found within 58 through 108 days after infection.5) Necator americanus was obtained from the four volunteers by expelling; 24, 21, 3 and 7 respectively.6) The rate of collected Necator americanus to the larvae applied was 13.8%, 14.7%, 0, 2% and 3.3%.II The larvae of N. a. were applied to oral membranes for 90 seconds in 2nd experiment.1) No infection was observed in all four volunteers.2) No one complained of subjective symptoms in the time period up to expelling.3) Change in the blood picture was not observed for all four cases.4) No Necator americanus could be collected by expelling in all four cases.
日本衛生学会の論文