METHOD FOR THE ASSAY OF THE SUPPRESSIVE ACTION OF CORTICOSTEROIDS ON ADRENAL RESPONSIVENESS
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概要
- 論文の詳細を見る
A new method has been developed for measuring the adreno-cortical suppressive action of corticosteroids.This method rests on measuring <I>in vitro</I> steroidogenesis brought about by a standard dose of ACTH in the adrenals of rats treated with various doses of steroids. According to the obtained results, calculated as pharmacological and therapeutical equivalents, hydrocortisone and prednisolone possess similar efficiency, where, the action of dexamethasone is approximately twice higher.<BR>Accuracy of the method has been checked by the aid of statistical evaluation.
- 社団法人 日本内分泌学会の論文
著者
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FEKETE G.
Chemical Works of Gedeon Richter, Ltd., Hormone Department
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GÖRÖG P.
Chemical Works of Gedeon Richter, Ltd., Hormone Department