ESTROGEN POTENTIATION OF THE EFFECT OF THYROTROPHIN ON THYROID <SUP>131</SUP>I UPTAKE IN HYPOPHYSECTOMIZED FEMALE RATS
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概要
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The daily administration of β-estradiol benzoate (50μg or I mg) to hypophysectomized female rats for five consecutive days did not markedly alter <SUP>131</SUP>I uptake by the thyroid gland. Estrogen or PMS increased thyroid uptake of <SUP>131</SUP>I in TSH treated hypophysectomized rats. Similar results were obtained with estrogen but not PMS in hypophysectomized and oophorectomized animals. These observations show that estrogen can potentiate the TSH induced uptake of <SUP>131</SUP>I by an extrapituitary mechanism.
- 一般社団法人 日本内分泌学会の論文