STUDIES ON ACID MUCOPOLYSACCHARIDES IN EXPERIMENTAL HYPER-AND HYPOPARATHYROIDISM
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概要
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Changes in acid mucopolysaccharide metabolism were studied using<SUP>35</SUP>S-sodium sulfate in experimental hyper-and hypoparathyroidism in rats. Urinary excretion of<SUP>35</SUP>S, reaching the maximum 12 hrs. after the administration of isotope, was higher in hyperparathyroidism and lower in hypoparathyroidism than in controls. In bone tissue, <SUP>35</SUP>S activity showed a marked increase in the groups with parathyroid extract administration, especially in the incisor and epiphyses during the process of growth. The concentration of<SUP>35</SUP>S also increased in the kidney, liver, muscle and skin in hyperparathyroidism, while the slight changes or a tendency to decrease was seen in hypoparathyroidism.<SUP>35</SUP>S in serum albumin andγ-globulin fractions increased in hyperparathyroidism and showed a tendency to slight decrease in hypoparathyroidism.<SUP>35</SUP>S inα-globulin increased and<SUP>35</SUP>S in β-globulin showed a decrease in all experimental animals as compared with controls.
- 社団法人 日本内分泌学会の論文
著者
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Shimada Osamu
Department Of Anatomy Yamanashi University School Of Medicine
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SHIMADA OSAMU
Department of 1st Surgery, Iwate Medical University Medical School
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- STUDIES ON ACID MUCOPOLYSACCHARIDES IN EXPERIMENTAL HYPER-AND HYPOPARATHYROIDISM