Histological Changes of the Contralateral Adrenal Cortex in Acute sand Subacute Phases of Unilateral Adrenalectomy in Rats, with Special Reference to the Mode of Compensatory Hypertrophy

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概要

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• Acute, subacute and chronic changes in the adrenal of unilaterally adrenalectomized rats were investigated by means of histological observations as well as measuring the adrenal weights and cholesterol contents. The adrenal weights increased after the third postoperative day. The cholesterol concentrations declined gradually in the first 6 hrs., then temporarily recovered in 3 days and again dropped in 7 days. Acute histological changes were induced in one hr. after the operation, and evolutionary arrangements of vertical cell-columns in the entire cortex were made as early as 60 mins. In a few hrs. after the operation, there developed new, immature glomeruli, “blastema”, which piled up in connective tissues of a thickened capsule and grew in size to be combined with cell-columns of the fasciculata. These pilings and subsequent combinations in subacute and chronic phases seem to result in adrenal compensatory enlargement. Acute definite histological changes were demonstrated to be synchronized by the acute decline of cholesterol concentration ratios.

• 社団法人 日本内分泌学会の論文

著者

• OMOTO TSUGUO

  Department of Anatomy, Jikei University School of Medicine

関連論文

• FUNCTIONAL SIGNIFICANCE OF THE TUBULAR AGRANULAR ENDOPLASMIC RETICULUM IN THE ADRENOCORTICAL CELLS OF ALBINO RATS
• Effect of CRF on the Morphological and Functional Differentiation of the Cultured Chromophobes Isolated from Rat Anterior Pituitaries
• Histological Changes of the Contralateral Adrenal Cortex in Acute sand Subacute Phases of Unilateral Adrenalectomy in Rats, with Special Reference to the Mode of Compensatory Hypertrophy

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