Influence of Dexamethasone on TRF Induced TSH Release in Rats

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概要

• 論文の詳細を見る

• The effect of dexamethasone pretreatment on TSH release induced by synthetic TRF was investigated in rats.<BR>Plasma TSH levels were measured by means of McKenzies method with a slight modification.<BR>Dexamethasone was injected 4 hours before TRF administration. Blood samples were withdrawn from the jugular vein 10 min after TRF injection.<BR>In a group received single dexamethasone pretreatment, TSH release following the TRF administration was significantly enhanced when compared with those observed in the saline pretreated group.<BR>However, the increase in TSH release was not observed in the rats treated chronically by dexamethasone for 15 days.<BR>The mechanism responsible for this dexamethasone effect on TSH secretion induced by TRF exists at hypothalamic level.

• 社団法人 日本内分泌学会の論文

著者

• Sakoda Masahiro

  2nd Department Of Internal Medicine Kobe University School Of Medicine

• Fukatsu Hiroyoshi

  2nd Department of Internal Medicine, Kobe University School of Medicine

• BABA SIGEAKI

  2nd Department of Internal Medicine, Kobe University School of Medicine

• Fukatsu Hiroyoshi

  2nd Department Of Internal Medicine Kobe University School Of Medicine

• SAKODA MASAHIRO

  2nd Department of Internal Medicine, Kobe University School of Medicine

関連論文

• Factors Influencing Pituitary TSH Secretion in the Early Stage of Cold Exposure
• Influence of Dexamethasone on TRF Induced TSH Release in Rats

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