Induction of Ovulation by Synthetic Luteinizing Hormone Releasing Factor (LH-RF) in Various Stages of 4-day Cyclic Rats and Mice

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概要

• 論文の詳細を見る

• Effective doses of synthetic LH-RF for induction of ovulation at various stages, except the stage of estrus, of 4-day cyclic rats and mice were investigated. In rats injected subcutaneously at 4p.m., the maximal effective doses were 6.4μg on mtestrus, 0.8μg on diestrus, and 0.2μg on proestrus (proestrus rats were pretreated with pentobarbital). In mice the corresponding doses were 0.05μg on diestrus, and 0.02μg on proestrus. On metestrus, however, most of the mice ovulated by 0.4μg, while even larger doses up to 1.6μg failed to elicit ovulation in the others.

• 社団法人 日本内分泌学会の論文

著者

• OKAMOTO MICHIO

  Research Laboratories, Chugai Pharmaceutical Co., Ltd.

• NOBUNAGA TOSHIMA

  Research Laboratories, Chugai Pharmaceutical Co. Ltd.

• Okamoto Michiko

  Research Laboratories, Chugai Pharmaceutical Co., Ltd.

関連論文

• Delay in Ovulation with Pentobarbital Anesthesia Applied at Various Stages of the 4-Day Cyclic Rat
• Induction of Ovulation by Synthetic Luteinizing Hormone Releasing Factor (LH-RF) in Various Stages of 4-day Cyclic Rats and Mice
• Synthesis and Release of Prolactin in vitro from the Anterior Pituitary of Mouse During Estrous Cycle

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