Effects of microinjection of various prostaglandins into the 3rd ventricle, median eminence and pituitary on plasma LH in rats.

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概要

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• The effects of microinjection of PGs (PGE1, E2, F2a) into the 3rd ventricle, median eminence (ME) and anterior pituitary on plasma LH in rats were investigated.<BR>Blood samples were obtained by jugular puncture before, and 10 and 45 min after the injection of PGs (50 or 100μg). Plasma LH was measured by radioimmunoassay.<BR>In the 3rd ventricle microinjection, PGE2 produced a significant rise in plasma LH. PGE1 and F2a did not significantly alter plasma LH levels.<BR>In the median eminence, PGE2 and El produced a significant rise in plasma LH. PGF2a did not alter plasma LH levels.<BR>In the pituitary, PGE2 and El produced a significant rise in plasma LH. PGF2a did not alter plasma LH levels.<BR>These observations indicate that PGs act directly on the hypothalamic-pituitary axis, and that particular PG may be involved in the release of particular hormones from the hypothalamus and pituitary.

• 社団法人 日本内分泌学会の論文

著者

• Igarashi Masao

  The Department Of Internal Medicine St. Luke's International Hospital

• SATO TSUNEHARU

  The Department of Obsterics and Gynecology, Gunma University School of Medicine

• IGARASHI MASAO

  The Department of Obsterics and Gynecology, Gunma University School of Medicine

• HIRONO MASAHIRA

  The Department of Obsterics and Gynecology, Gunma University School of Medicine

• Jyujo Toshikuni

  The Department of Obsterics and Gynecology, Gunma University School of Medicine

関連論文

• Electrocardiogram in Potassium Depletion Part 1 : Electrocardiographic Patterns in Acute and Chronic Potassium Deficiency
• Electrocardiogram in Potassium Depletion : Part II: Atrial and Nodal Tachycardia in Digitalis Intoxication
• Effects of microinjection of various prostaglandins into the 3rd ventricle, median eminence and pituitary on plasma LH in rats.

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