Immune Complexes in Diabetes Insipidus Syndrome of Rabbits Immunized with Vasopressin
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概要
- 論文の詳細を見る
Rabbits immunized with lysine-vasopressin bovine serum albumin conjugate showed the diabetes insipidus syndrome intermittently manifested by polyuria and polydipsia with various degrees of peaking from the eighth to fourteenth day post injection during boosters.<BR>The antibody-antidiuretic hormone immune complexes which may interfere with the action of the endogenous vasopressin on the kidney were found in the diabetes insipidus rabbits. However, the degree of the polyuria was not necessarily related to the quantities of the formed immune complexes, the titer, nor the affinity of the antiserum. It is suggested that the degree of the polyuria is related not only to the binding ability of the antiserum to the endogeneous vasopressin, but also to other factors.
- 社団法人 日本内分泌学会の論文
著者
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ITO SEIKI
The First Department of Internal Medicine, Niigata University School of Medicine
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KAMOI KYUZI
The First Department of Internal Medicine, Niigata University School of Medicine
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HAMA HITOSHI
The First Department of Internal Medicine, Niigata University School of Medicine
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MATSUOKA MATSUZO
The First Department of Internal Medicine, Niigata University School of Medicine
関連論文
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- Immune Complexes in Diabetes Insipidus Syndrome of Rabbits Immunized with Vasopressin
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