Studies on the “Low Dose” Suppressible Cushings Disease

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概要

• 論文の詳細を見る

• Diagnosis of Cushings disease in most cases can be established by the standard dexamethasone suppression test without difficulty. However, some cases were known to be normally suppressed by the standard low dose of dexamethasone (2mg daily). The case we encountered recently was also normally suppressed by either the rapid (Nugent) or the standard (Liddle) method. This fact prompted us to study the usefulness of a single dose of 0.5mg of dexamethasone to suppress the plasma cortisol in the normal.<BR>It was concluded that the single oral dose of 0.5mg of dexamethasone given at 11 p.m. on the previous night suppressed the plasma cortisol efficiently the following morning in the normal, thus making the differentiation of particular cases of Cushings disease from the normal possible. The disappearance of plasma dexamethasone did not differ significantly between the normal and the Cushings disease.

• 社団法人 日本内分泌学会の論文

著者

• SHIMIZU NAOKATA

  The First Department of Medicine, Teikyo University, School of Medicine

• YOSHIDA HISAYOSHI

  The First Department of Medicine, Teikyo University, School of Medicine

• SHIMIZU NAOKATA

  The First Department of Internal Medicine, Teikyo University, School of Medicine

• YOSHIDA HISAYOSHI

  The First Department of Internal Medicine, Teikyo University, School of Medicine

関連論文

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• Studies on the “Low Dose” Suppressible Cushings Disease
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