Effect of Cytidine Diphosphate Choline on Growth Hormone and Prolactin Secretion in Man

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概要

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• The effect of intravenous infusion of cytidine diphosphate choline (CDP-choline) on the serum levels of growth hormone (GH) and prolactin (PRL) was studied in six normal adult male subjets. Serum GH levels increased and reached a maximum at 60-90min after the initiation of infusion in all subjects examined. The mean peak value of GH in six subjects was 10.0±2.1 (mean±SE) ng/ml, which was significantly higher than the basal level (p<0.01). In four subjects, serum PRL levels decreased from 10-24ng/m<I>l</I> to less than 7.2 ng/m<I>l</I> at 60-120 min, while in the other two no significant change was observed. These results indicate that CDP-choline affects GH and PRL secretion from the anterior pituitary.

• 社団法人 日本内分泌学会の論文

著者

• Nagai Kiyoyasu

  Second Department Of Internal Medicine Hyogo Colege Of Medicine

• MATSUOKA TOHRU

  Second Department of Internal Medicine, Hyogo College of Medicine

• KAWANAKA MASAHIRO

  Second Department of Internal Medicine, Hyogo College of Medicine

• NAGAI KIYOYASU

  Second Department of Internal Medicine, Hyogo College of Medicine

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