The Leucocyte Migration Inhibition Test and Subpopulations of Peripheral Lymphocytes in Insulin-Dependent Diabetics
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概要
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The leucocyte migration inhibition test (LMT) was performed by the agarose plate method with thyroid and pancreatic antigens in patients with insulin-dependent or independent diabetes mellitus. The mean migration indices with thyroglobulin, thyroid mitochondria and beef insulin were not significantly different in insulindependent diabetics from those in insulin-independent diabetics or normal controls.<BR>However, significant inhibition of leucocyte migration was observed in insulindependent diabetics when thyroid microsome or pancreatic extract was used as antigen. Although no significant difference was found in the percentages of T and B lymphocytes between insulin-dependent diabetics and insulin-independent diabetics or normal controls, the results of LMT strongly suggest the presence of cellular immunity against the thyroid and pancreas in insulin-dependent juvenile-onset diabetes.
- 社団法人 日本内分泌学会の論文
著者
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IMURA Hiroo
2nd Div.,Dept.of Medicine,Kyoto Univ.Sch.of Med.,and Div.of Cardiology,Kumamoto Univ.Sch.of Med.,
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SAKURAMI TAKEHIKO
2nd Department of Internal Medicine, Faculty of Medicine, Kyoto University
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NAGAOKA KENGO
2nd Department of Internal Medicine, Faculty of Medicine, Kyoto University
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NABEYA NOBORU
2nd Department of Internal Medicine, Faculty of Medicine, Kyoto University
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KUNO SHOTARO
Osaka Red Cross Hospital
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