Effects of Oral Administration of Trypsin Inhibitor and Repeated Injections of Pancreozymin on the Insulin and Glucagon Contents of Rat Pancreas

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概要

• 論文の詳細を見る

• Rats were given soybean trypsin inhibitor or repeatedly injected with pancreozymin (daily 40 I.D.U./kg) for 7 days, and the insulin and glucagon contents of the pancreas were measured. The insulin and glucagon contents were markedly increased after these treatments and this effect was especially conspicuous after injections of large doses (daily 120 I.D.U.) of depot-type pancreozymin. Insulin content thus reached 1.9times, and glucagon content 2.4times as much in control values. This result is compatible with our previous histological finding that not only the exocrine pancreas but also islet cells undergo the trophic effect of endogenous and exogenous pancreozymin.

• 社団法人 日本内分泌学会の論文

著者

• MATSUNARI YOKO

  Department of Anatomy, Niigata University School of Medicine

• HAYASHI MUTSUKO

  1st Department of Internal Medicine, Niigata University School of Medicine

• KOGA YUKICHI

  Shimizu-Seiyaku Pharmaceutical Company

関連論文

• Effects of Oral Administration of Trypsin Inhibitor and Repeated Injections of Pancreozymin on the Insulin and Glucagon Contents of Rat Pancreas

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