Inhibition of Thyroxine-Induced Metamorphosis by Prolactin in Tadpoles, <I>Rana Catesbeiana</I>
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概要
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Thyroxine (T4)-prolactin interactions on hepatic arginase and ornithine transcarbamylase (OTC) as well as hind legs, tail, digestive tract and median eminence were investigated in tadpoles, <I>Rana catesbeiana</I>.<BR>Prolactin completely blocked T4-induced tail resorption, but failed to suppress hind-leg growth, shortening of digestive tract and promotion by T4of the median eminence development. Prolactin blocked T4-induced increase in hepatic arginase activity but not in hepatic OTC activity.<BR>A possibility that T4and prolactin are regulating the hepatic arginase indirectly is discussed.
- 社団法人 日本内分泌学会の論文