Enhancement of DMBA Induced Mammary Tumours by Intermittent Whole Body Hyperthermia (42°C)

スポンサーリンク

概要

• 論文の詳細を見る

• Wistar Female rats bearing DMBA induced mammary tumours were subjected to whole body hyperthermia 42°C dry heat exposure for 15 minutes daily for 6 weeks. The control group was maintained at a room temparature of 25°C. Hyperthermia induced significant growth stimulation of breast tumour compared to the controls. Plasma estradiol was slightly decreased while total T<SUB>4</SUB> and TSH values remained unchangedin heat stressed rats. Plasma prolactin was significantly increased together with enhanced synthetic activity of pituitary prolactin cells. It is concluded that heat acting as stressor accelerates breast tumor growth, probably by influencing synthesis of prolactin. Therefore the hormone dependancy of tumours should be considered before hyperthermia is used as an anticancer modality.

• 社団法人 日本内分泌学会の論文

著者

• LAHIRI TWISHA

  Chittaranjan National Cancer Research Centre

• DEOMINA NATASHA

  Cancer Research Centre, Academy of Medical Sciences

• DEDOV IVAN

  Cancer Research Centre, Academy of Medical Sciences

• LAHIRI PULAK

  Univ. of Calcutta

関連論文

• Enhancement of DMBA Induced Mammary Tumours by Intermittent Whole Body Hyperthermia (42°C)

スポンサーリンク