Factitious Bartters Syndrome Induced by Surreptitious Intake of Furosemide
スポンサーリンク
概要
- 論文の詳細を見る
Studies on the electrolyte metabolism and the renin-angiotensin-aldosterone system were made in a 47-year-old female patient with factitious Bartters syndrome induced by surreptitious use of furosemide. The diagnosis was confirmed later by detection of the diuretic in the urine. In metabolic studies patient exhibited abnormalities similar to those reported in Bartters syndrome; viz, hypokalemic alkalosis, blunted response to exogenous angiotensin II, which reverted to normal by volume expansion with an albumin solution, and diminished fractional free water clearance per fractional distal sodium delivery. The above data, along with the known pharmacological effects of furosemide, suggest that the abnormality in Na<SUP>+</SUP> or Cl<SUP>-</SUP> reabsorption in the ascending limb of Henles loop is a primary cause of Bartters syndrome.
- 社団法人 日本内分泌学会の論文
著者
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Isozaki Sadao
Hospital Pharmacy Faculty Of Medicine University Of Tokyo
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UCHINO KATSUYOSHI
Hospital Pharmacy
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FUJITA TOSHIRO
Institute of Clinical Medicine, University
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SEKINE KAZUO
From the Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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KOJIMA ITARU
From the Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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OGATA ETSURO
From the Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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ISOZAKI SADAO
Hospital Pharmacy, the University of Tokyo
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UCHINO KATSUYOSHI
Hospital Pharmacy, the University of Tokyo
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FUJITA TOSHIRO
Institute of Clinical Medicine, University of Tsukuba
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