The Effect of Ovarian Hormones on Stress Relaxation in the Uterus of the Pregnant Rat

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概要

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• Tissue strip taken from rat uterine ampulla on day 20 of pregnancy was elongated at a constant rate in Tyrodes solution at 37°C to the length of a specified peak stress, and the stress decline was recorded at this length. The stress decline in uterine strips of ovariectomized progesterone-treated rats was significantly slower than those in intact pregnant rats at any different peak stress and elongation rate examined. Treatment with estradiol as well restored the physical properties to the control levels. Changing the medium to Ca-free Tyrodes solution had no effect on stress relaxation. Results suggest that estrogen with progesterone improves stress relaxation in the rat uterus during late pregnancy by changing the state of the noncontractile elements in the tissue.

• 社団法人 日本内分泌学会の論文

著者

• TAMADA Hiromichi

  Laboratory of Theriogenology, Graduate School of Agriculture and Biological Sciences, Osaka Prefectu

• ICHIKAWA SHIGETAKA

  Laboratory of Animal Reproduction, College of Agriculture, University of Osaka Prefecture

• TAMADA HIROMICHI

  Laboratory of Animal Reproduction, College of Agriculture, University of Osaka Prefecture

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• The Effect of Estrogen on Fetal Survival in Progesterone-Treated Ovariectomized Rats
• The Effect of Ovarian Hormones on Stress Relaxation in the Uterus of the Pregnant Rat
• Effect of Incubation with NADPH Generator on Progesterone Bound to Nuclei of the Rat Uterus
• Effect of the Placenta on the Growth and Function of Artificially Formed Secondary Corpora Lutea of Pregnancy in Rats

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