Histochemical Location of 17β-Hydroxysteroid Oxidoreductase in The Adult and Infantile Human Testis

スポンサーリンク

概要

• 論文の詳細を見る

• 17β-Hydroxysteroid oxidoreductase in the human testis was investigated histochemically using tissues obtained from seven patients with undescended testis or varicocele at the time of orchiopexy or high ligation of spermatic vein. Formazan precipitates were formed from nitro-blue tetrasolium in the tissue utilizing hydrogen released by oxidation of testosterone, which is catalized by the reductase function of 17β-hydroxysteroid oxidoreductase. The precipitates were formed specifically in the presence of 17β-hydroxy-C<SUB>19</SUB>-steroids under the conditions employed in the present study. In infantile testes, the precipitates were formed in cytoplasm of immature Sertoli cells, while in pubertal or adult testes, marked formazan precipitates were found in cytoplasm of both Sertoli and Leydig cells. The results indicate the presence of two distinct 17β-hydroxysteroid oxidoreductases in the human testis; one in Sertoli cells and detectable independent of age and the other only in functional Leydig cells.

• 社団法人 日本内分泌学会の論文

著者

• OSHIMA Hiroyuki

  Department of Urology Tokyo Medical and Dental University School of Medicine

• Higashi Yotsuo

  Department Of Urology Saitama Cancer Center

• HATAKEYAMA SHIGERU

  Departments of Pathology Tokyo Medical and Dental University School of Medicine

• Oshima Hiroyuki

  Department Of Blood Purification And Department Of Urology Tokyo Medical And Dental University

• HIGASHI YOTSUO

  Departments of Urology Tokyo Medical and Dental University School of Medicine

関連論文

• Chromophobe Cell Renal Carcinoma in Childhood
• Molecular Cloning of a Putative Gastric Chitinase in the Toad Bufo japonicus(Biochemistry)
• ISOLATION, CHARACTERIZATION AND cDNA CLONING OF A NOVEL PANCREATIC CHITINASE OF THE TOAD BUFO JAPONICUS
• Yolk sac tumor but not seminoma or teratoma is associated with abnormal epigenetic reprogramming pathway and shows frequent hypermethylation of various tumor suppressor genes
• Cutaneous Hemangioma of the Penis Successfully Treated with Sclerotherapy and Ligation
• Cardiovascular events in survivors of high-dose chemotherapy for germ cell tumors
• DIRECT PROJECTION OF A SUBSET OF PRIMARY OLFACTORY NEURONS TO THE POSTERIOR PARTS OF THE BRAIN OF THE TOAD, BUFO JAPONICUS
• Rapid and selective removal of larval erythrocytes from systemic circulation during metamorphosis of the bullfrog, Rana catesbeiana
• Detection of Disseminated Urothelial Cancer Cells in Peripheral Venous Blood by a Cytokeratin 20-specific Nested Reverse Transcriptase-Polymerase Chain Reaction
• Possible misinterpretation on computed tomography of left inferior vena cava as retroperitoneal lymph node metastasis:A report of two cases
• Secondary Treatment Failure without Anti-human Chorionic Gonadotropin Antibody in a Patient with Kallmann Syndrome
• Stronger Suppression of Serum Testosterone and FSH Levels by a Synthetic Estrogen than by Castration or an LH-RH Agonist
• Bacillus Calmette-Guerin Enhances Production and Secretion of Type IV Collagenases in Peripheral Blood Mononuclear Cells
• Chlormadinone Acetate as a Possible Effective Agent for Congenital Adrenal Hyperplasia to Suppress Elevated ACTH and Antagonize Masculinization
• Ureteroarterial Fistula after Urinary Diversion
• Telomere Length and Telomerase Activity in Bladder and Prostate Cancer Cell Lines
• Clinical outcome of chemoradiotherapy for T1G3 bladder cancer
• Incorporation of TIP (paclitaxel, ifosfamide, cisplatin) into first-line therapy for intermediate to poor risk testicular germ cell tumors with unfavorable marker decline after initial two cycles chemotherapy : A report of three cases
• Histochemical Location of 17β-Hydroxysteroid Oxidoreductase in The Adult and Infantile Human Testis
• Oral fluid removal by water-adsorbent polymer for end-stage renal disease
• A Further Study of17β-Hydroxysteroid Oxidoreductase in the Human Testis: Mechanism of In Vitro Activation
• Organogenesis, Descent and Regression of the Testis
• In vitro steroidogenesis in testes of three infants, two with ambiguous external genitalia and one with true precocious puberty: Evidence for the presence of active 17.BETA.-hydroxysteroid oxidoreductase in immature human testes.
• A Comparative Study of Steroid Biosyntheses in Vitro. in Clear Cell Adenoma and its Adjacent Tissue of Human Adrenal Gland
• Dissociation of Magnitude of Relaxation from cyclic AMP Levels in Rabbit Urinary Bladder Smooth Muscles.

もっと見る 閉じる

スポンサーリンク