ÜBER DIE WIRKUNG VON KALHKREIN AUF DIE FUNKTION DES HYPOPHYSE-GONADENSYSTEMS
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概要
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The effect of kallikrein on the pituitary-gonadal function was investigated in rats.<BR>In female rats the ovarian and uterine weights showed a significant increase after 30 day kallikrein treatment.Adrenal and thyroid weights and tail length increased significantly only in a few sections of the experiments. No change in <SUP>131</SUP>I uptake and T/S ratio of the thyroid was noted.<BR>In male rats only the prostate and seminal vesicles showed a significant weight gain but not the other organs.<BR>In hypophysectomized rats the weights of ovary, uterus, adrenals and thyroids were not significantly different between the kallikrein administered group and the control.<BR>Pituitary gonadotrophic potency as measured by the mouse-uterine-weight method was augmented by kallikrein both in female and male rats.<BR>It seems reasonable to conclude from these results that kallikrein has an effect to augment the production and release of pituitary gonadotrophin.
- 社団法人 日本内分泌学会の論文
著者
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SATO SHOGO
Frauenklinik, Gunma Universität
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SATO TSUNEHARU
Frauenklinik, Gunma Universität
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Igarashi M.
Frauenklinik, Gunma Universität
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KUBO HIROSHI
Frauenklinik, Gunma Universität
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KUBO HIROSHI
Frauenklinik, Gunma Universität
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IGARASHI MASAO
Frauenklinik, Gunma Universität