HISTOCHEMISCHE UNTERSUCHUNGEN ÜBER DIE ENDOMETRIALE CARBOANHYDRASE DES KANINCHENS

スポンサーリンク

概要

• 論文の詳細を見る

• The biochemical and histochemical investigations presented in this paper confirm that progesterone administered into the estrogen-primed immature female rabbit produces marked increase of carbonic anhydrase in the endometrium.<BR>It is clearly demonstrated that the increases of carbonic anhydrase induced by progesterone takes place in the glandular portion of uterine mucosa and the precipitation of manganese granules resulting from the enzyme reaction are concentrated in the epithelial cells.<BR>Acetazoleamide administered intravenously 30 mins. before autopsy causes marked reduction of endometrial carbonic anhydrase activity and poor stainning of the uterine section prepared by the Hauslers (1958) cobalt sulfate method for carbonic anhydrase.<BR>Comparing the enzyme activity of one horn perfused with saline before the enzyme extraction with that of the other horn without perfusion on the same uterus, the activities derived from the blood contaminated in the extracts are investigated for a series of control and progesterone-treated groups. The data demonstrate that the rate of enzyme activity resulted from blood contamination in the extract of progesterone-treated group is rather smaller than that in the control group.<BR>It is, therefore, concluded that the increase of endometrial carbonic anhydrase in the Clauberg rabbit treated with progesterone is probably due to the new biosynthesis of the enzyme in the epithelial cells of uterine mucosa.

• 社団法人 日本内分泌学会の論文

著者

• NAGATA GENJI

  Endokrinologische Abteilung, Shionogi-Institut

• MIYAKE TAMOTSU

  Endokrinologische Abteilung, Shionogi-Institut

• Nagata G.

  Endokrinologische Abteilung, Shionogi-Institut

関連論文

• HISTOCHEMISCHE UNTERSUCHUNGEN ÜBER DIE ENDOMETRIALE CARBOANHYDRASE DES KANINCHENS

スポンサーリンク