ヌクレオシドのホスホリル化法における最近の進歩

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概要

• 論文の詳細を見る

• The phosphorylation of nucleosides is a fundamental reaction in the synthesis of oligonucleotides. This article reviews recent results on the phosphorylation of nucleosides in the synthesis of oligonucleotides by the phosphotriester method and the phosphite triester method. The new condensing and phosphorylating reagents for modified phosphotriester method, activated phosphotriester method, and modified phosphite triester method were discussed.

• 社団法人 有機合成化学協会の論文

著者

• 高久 洋

  Department of Chemistry, Chiba Institute of Technology

• 高久 洋

  Department of Chemistry, King's College London

関連論文

• Reaction of the Salt of N-Phosphoryl-N'-methylimidazole and Its Application to the Synthesis of Monoalkyl Dihydrogen Phosphates
• A Simple Synthesis of Nucleoside Phosphates
• Phosphorylation by Active Ester of Phosphoric Acid. I. Preparation and Reaction of Phenyl 8-Quinolyl Phosphate
• ヌクレオシドのホスホリル化法における最近の進歩

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