含硫アミノ酸のジクロルアセチル化
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概要
- 論文の詳細を見る
Cancer inhibitors may be mentioned as one of the most urgently needed chemicals at present. It was found that a certain amino acid showed carcinogenic inhibition. In this report, the synthesis of sulfur-containing amino acids, especially of dichloroacetyl derivatives are described. Methionine, its oxidized substances and its esters, cysteine, cystine and its esters were selected as starting materials. Their acylations were made by (A) Schotetn-Baumanns method and (B) by Kamedas method. The results indicated that the sulfur-containing amino acids in general gave higher yield and higher purity of objective compounds in the B method than in the A method, while the synthesis was easier by use of the A Method in case of esters.
- 社団法人 有機合成化学協会の論文
著者
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佐々木 正
Institute Of Applied Organic Chemistry Faculty Of Engineering Nagoya University
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佐々木 正
東京理科大学薬学部
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兼松 顕
東京理科大学薬学部
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榊原 雅子
東京理科大学薬学部
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- 含硫アミノ酸のジクロルアセチル化