シスプラチン類縁体の合成研究
スポンサーリンク
概要
- 論文の詳細を見る
Cisplatin [<I>cis</I>-dichlorodiammineplatinum (II)] has been widely used for clinical cancer chemotherapy though the complex has severe side effect such as renal toxicity. This article is summarized synthetic method, reactivities, and mechanism of action against target molecules of cisplatin. And a part of newly synthesized cisplatin analogs including our liposoluble or water miscible platinum (II) complexes are summarized with their antitumor activities against experimental tumors.
- 社団法人 有機合成化学協会の論文