遺伝子操作による物質生産の現状と将来
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概要
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Industrial microorganisms have been improved mainly by mutation and selection for their productivity, but recent development of gene manipulation would offer more effective tool for microbial breedings. Since the primary gene products are polypeptides, the gene manipulation techniques have been mainly applied to produce human peptide hormones, interferons and enzymes. These polypeptides have been expected to be useful for therapy of human diseases in near future. The technique will be available also to improve biomass production including microorganisms and plants. Further application is planned in the field of chemical industry, such as the conversion of ethylene to ethylene oxide. In addition, this technique would be developed as tolls for breeding of industrial microorganisms, especially in Japan.
- 社団法人 有機合成化学協会の論文