合成化学的方法と生物化学的方法 (生物を利用する有機合成と有用物質の生産特集号)
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概要
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Scope and limitations of chemical and biochemical methods are generally described. Chemical methods can be widely used for the preparation of various and abundant compounds, for instance by using high temperature, high pressure, strong bases and the elements such as rhodium and palladium which are not utilized by living things.<BR>On the contrary, biochemical methods are chiefly used for the preparation of optically active compounds, by using enzymes which catalyze the asymmetric reactions under mild conditions.<BR>As an example, chemical and biochemical preparations of DL- and D (L) -α-hydroxyacids from aldehydes or esters by one carbon homologation are comparatively stated.
- 社団法人 有機合成化学協会の論文