The Bactericidal Activity of Monobasic Fatty Acids on some Putrefactive and Pathogenic Bacteria. II
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概要
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In the previous paper(2), I have reported the bactericidal activity of saturated monobasic fatty acids (C1-C10) on Staphylococcus pyogenes aureus, Proteus vulgaris HAUSER, Bacillus typhosus and Vibrio cholerae. The present paper deals with the bactericidal activity of saturated monobasic higher fatty acids (C11-C18) on the above-mentioned kinds of bacteria using the method described in the previous paper(1). The results obtained are summarized as follows:- (1) As regards the bactericidal activity of the saturated solutions of acids, from undecylic acid (C11) to stearic acid (C18), undecylic acid leads the list, and lauric acid comes next. The acids with C14-C18 have no bactericidal power, but even afford better conditions to microorganisms for sustaining life. (2) Hydrogen-ion, dissociated from acids, concerns little with the bactericidal action of these acids. (3) Anions of C11-C12 acids have bactericidal power to a certain measure. (4) Among Na-, Ca-and NH4-salts, the last one has the weakest bactericidal power. (5) Undissociated molecules have also remarkable effects on the bactericidal activites of undecylic and lauric acids.
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