経口投与による水銀の魚体内分布
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概要
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During several years since 1953, there happened a certain disease, neurologic disorder, in the vicinity of Minamata City, Kumamoto Prefecture. It is thought that the disease was due to eating fish which was made poisonous by mercury widely distributed in the Minamata Bay. Tissue distribution of mercury orally given to fish is now reported. Sea mussel concentrated mercury 660 times in 4 days and short-necked clam concentrated the element 190 times in 8 days when these shellfish were kept in sea water to which 203Hg labeled mercuric chloride had been added to give a concentration of 0.05mg. per liter (Table 1). No significant difference on the patterns of distribntion of mercury in tissues was shown between the carp fed with the sea mussel for 17 days and the conger eels fed with the shortnecked clam for 11 or 19 days. Accumulation of mercury in the brain was not found but the high concentration of the element in the kidney, gills and liver was noted, and obvious existence of mercury in the bone was also recognized. Values of the mercury content in the muscle were low, ranging from 0.03 to 0.5μg. per g. (Table 2 and 3). The present result does not coincide with that of the study on the mercury content of fish collected in the Minamata Bay, in which the mercury content in the muscle were given to be fairly high. This presumably in dicates that the chemical form of mercury in the tissues of shellfish which was given to the fish in the present study was different from that of mrcury in the food taken by fish in the Minamata Bay. It is thought that the most part of mercury taken up by the shellfish from sea water to which mercuric chloride was added had not developed into organic mercury compound.
- 公益社団法人 日本水産学会の論文
著者
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