The Bactericidal Activity of Monobasic Fatty Acids on Some Putrifactive and Pathogenic Bacteria

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概要

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• The present paper deals with the bactericidal activity of saturated monobasic acids (CnH2n+1COOH) on Staphylococcus pyogenes aureus, Proteus vulgaris, Hauser, Bac. typhosus and Vib. cholerae. The methods and experimental conditions are the same as described in the previous paper.(1) When tested with the same concentration, the bactericidal activity is nearly the same in 6 acids-from acetic to isovaleric acids-and is less than that of formic acid. The activity in question increases, but solubility in water decreases, with the number of C-atoms of the acids higher than caproic acid (C8) when examined under the same pH-value, namely, it is extraordi narily strong in caprylic (C8), pelargonic (C9), and capric (C10) acids. It is always greater in the normal than in the iso-acids. Its greater activity is evident in the same concentration of mineral acids such as HNO3, HCl, H2SO4, H3PO4 than in C1-C5 acids. The bactericidal activity of monobasic acids has much to do with their undissociated molecules. This is especially the case with higher monobasic acids. The anions of monobasic acids have insignificant bactericidal activity but those of higher acids appear to show greater activity than those of lower acids as bactericides.

• 社団法人 日本水産学会の論文

著者

• 鐡本 總吾

  傳染病研究所

関連論文

• Dibasic Fatty Acids as Agents Destructive of Some Putrefactive and Pathogenic Bacteria
• The Bactericidal Activity of Monobasic Fatty Acids on Some Putrifactive and Pathogenic Bacteria

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