Osmotic sensitive characteristics of an LmpB mutant strain in cellular slime mould Dictyostelium discoideum

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概要

• 論文の詳細を見る

• As one of the cellular slime mould mutants produced with restriction enzymes mediated integration (REMI), we isolated a strain that carries an insertion mutation in LmpB gene. LmpB is a lysosomal protein and suggested to be involved in the endosome maturation. Although some regulatory components associated with endosomes are commonly found in the contractile vacuoles, LmpB has not been suggested to be involved in the process of the osmotic regulation. However, when LmpB mutant cells were placed under osmotic stress, they developed morphologically aberrant large vacuoles in the cytoplasm and the viability of the cells was significantly reduced. The result implies that LmpB is not only involved in the endosome maturation, but also involved in the function of contractile vacuoles.

• 日本植物形態学会の論文

著者

• Abe Tomoaki

  Department Of Biological Engineering Faculty Of Science And Engineering Ishinomaki Senshu University

• Sukegawa Maki

  Department of Biological Engineering, Faculty of Science and Engineering, Ishinomaki Senshu University

関連論文

• Morphological analysis of the gene-disruptants of the Dictyostelium discoideum Rap1-GAP homologue
• Osmotic sensitive characteristics of an LmpB mutant strain in cellular slime mould Dictyostelium discoideum

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