Interleukin-3 promotes neurite outgrowth and elevates choline acetyltransferase activity in vitro.

スポンサーリンク

概要

• 論文の詳細を見る

• Here we demonstrate that interleukin-3 (IL-3) promotes neurite outgrowth of neurons obtained from septal regions of mouse embryos using serum-free medium. Moreover, IL-3 elevates choline acetyltransferase (ChAT) activity in these neurons as well as in cholinergic neuronal line cells SN6.10.2.2. Since it is reported that astrocytes produce IL-3-like factors, these results indicate a possible trophic function of IL-3 for central cholinergic neurons in vivo.

• 日本学士院の論文

著者

• Tabira Takeshi

  Division Of Demyelinating Disease And Aging National Institute Of Neuroscience

• KUNISHITA Tatsuhide

  Division of Demyelinating Disease and Aging, National Institute of Neuroscience

• KAMEGAI Masahiro

  Division of Demyelinating Disease and Aging, National Institute of Neuroscience

• TOKUCHI Fumio

  Division of Demyelinating Disease and Aging, National Institute of Neuroscience

• NISHIZAWA Masatoyo

  Division of Demyelinating Disease and Aging, National Institute of Neuroscience

関連論文

• Decreased Expression of MAP-2 and GAD in the Brain of Cats Infected with Feline Immunodeficiency Virus
• Frontotemporal dementia with tauopathy : A review and preliminary immunohistochemical study of tau kinases and phosphatases
• Prophylactic and therapeutic effect of bactobolin on autoimmune encephalomyelitis.
• Interleukin-3 promotes neurite outgrowth and elevates choline acetyltransferase activity in vitro.

スポンサーリンク