MECHANISM OF THE APPEARANCE OF β-K BAND IN THE FRACTION OF LIPOPROTEIN BY POLYACRYLAMIDE GEL-DISC ELECTROPHORESIS AND THE FREQUENCY OF ITS APPEARANCE IN IHD

概要

論文の詳細を見る
A β-k band is one of β-lipoprotein which is separated into a few subunits by polyacrylamide gel-disc electrophoresis. The mechanism and the frequency of the appearance of β-k band in 140 patients were studied using disc electrophoresis and ultracentrifugation. The sample having this band was shown a lower TG/protein ratio in low density lipoproteine (LDL) as compared with those without β-k band. In the ratio of TCh/protein, these relations were reversed. In the ratio of TCh/TG in the fraction of very low density lipoprotein (VLDL), the sample with β-k band showed the values more than 0.35, whereas the sample without this band showed the values less than 0.35. According to these findings, the β-k band may be produced by an incomplete hydrolysis of TG in the raction of VLDL.The frequency of β-k band was significant difference between the patients with is chemic heart disease (HID) and the patients without IHD. IHD group showed the value of 31.2 %, control group was 17.6 %. This findings suggested that β-k band was more evident in the patients with IHD than those without IHD.
久留米大学医学部 The Kurume Medical Journal 編集部の論文