ULTRASTRUCTURE OF THE LIVER IN HUMAN AMYLOIDOSIS

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概要

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• The liver specimens obtained from two patients with primary amyloidosis were examined with light and electron microscopies. One patient, considered to be in the early stage, showed minimal deposits of amyloid in the portal area and space of Disse. The other, being in advanced stage, had massive deposits of amyloid through the entire lobules, and the hepatocytes seemed to be compressed by them, resulting in hepatocellular degeneration. The cellular origin of amyloid still remains uncertain. From this study, however, it seemed that the reticuloendothelial cell, especially Kupffer cell, has a close relation to amyloid production.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• Kimura Naomi

  Division Of Human Genetics National Institute Of Genetics

• OKUGAWA NORIHIRO

  Second Department of Internal Medicine

• EGUCHI TAKAHISA

  Second Department of Internal Medicine

• FUKUDA KAZUO

  Second Department of Internal Medicine

• TANIKAWA KYUICHI

  Kurume University School of Medicine

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• ULTRASTRUCTURE OF THE LIVER IN HUMAN AMYLOIDOSIS

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