Prognostic Efficacy of Treatment for Extrahepatic Metastasis after Surgical Treatment of Hepatocellular Carcinoma
スポンサーリンク
概要
- 論文の詳細を見る
The purpose of the present study was to investigate, retrospectively, the clinical significance of treatments for extrahepatic metastasis after surgical treatment of hepatocellular carcinoma (HCC). Forty-seven patients, in whom extrahepatic metastasis developed after hepatic resection or microwave coagulation therapy (MCT) for primary HCC, were enrolled in this study. Metastatic organs were lung (38 cases), bone (10 cases), brain (6 cases), adrenal gland (3 cases), and lymph nodes (9 cases), including duplicated cases. Twenty eight patients were treated with surgical resection, anticancer chemotherapy, radiation and immunotherapy for the extrahepatic metastasis (the treatment group). Nineteen patients were in no treatment except symptomatic therapy (the nontreatment group). The 1- and 3-year survival rates after development of extrahepatic metastasis in the treatment group were 42.3% and 17.8%, respectively. No patients in the non-treatment group survived more than 2 years. There was a significant difference between the treatment and the nontreatment group (p=0.0021) with regard to survival rate. Univariate analysis of the treatment group showed the following factors to be significant for survival: 1) intrahepatic lesion(s) was cleared or well controlled by some type of treatment, 2) the treatment for extrahepatic metastasis was effective, 3) extrahepatic metastasis was recognized in Grade A of Child-Pugh classification. Treatment of extrahepatic metastasis of HCC was of great significance for the prognosis.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
-
IMAMURA ICHIRO
Department of Surgery, Kurume University School of Medicine
-
Imamura Ichiro
Department Of Surgery And Science Graduate School Of Medical Sciences Kyushu University
関連論文
- Gastric enterochromaffin-like-cell tumor with liver and splenic metastases
- Surgical Resection Following Combination Chemotherapy with Oral S-1 and Biweekly Docetaxel in a Patient with Advanced Gastric Cancer and a Prior Coronary Artery Bypass Graft with the Right Gastroepiploic Artery : Report of a Case
- Endocrine Tumor of the Pancreas. An Evaluation of Eighteen Patients who Underwent Resection Followed by Long Term Survival.:An Evaluation of Eighteen Patients who Underwent Resection Followed by Long Term Survival
- Gastric Stromal Tumor with CD34 Immunoreactivity. A Case Report.:A Case Report
- A Long-Term Survival Patient with Advanced Gallbladder Cancer Massively Metastasizing to the Liver.
- A Resected Case of Pancreatic Metastasis from Primary Renal Cell Carcinoma.
- Prognostic Efficacy of Treatment for Extrahepatic Metastasis after Surgical Treatment of Hepatocellular Carcinoma
- A So-Called Carcinosarcoma of the Gallbladder in a Patient with Multiple Anomalies. A Case Report.:A Case Report
- Nonfunctioning Islet Cell Carcinoma. A Twenty-One Years Survival Case after Distal Pancreatectomy.:A Twenty-One Years Survival Case after Distal Pancreatectomy