THE EXPERIMENTS ON THE CARDIAC MUSCLE (2) THE EFFECT OF IONIC GRADIENT ACROSS MEMBRANE, ATP AND PYRUVIC ACID, ETC

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概要

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• Much information on the knowledge of the electrophysiology of single cardiac cells has, recently, been reviewed by Weidmann (1) or by Cranefield and Hoffman (2). The present experiments of the cardiac muscle have been performed as a serial investigation of the muscles in a living organism.The previous report by this author et al. (3) indicates the experiments on a heart muscle must be performed from two points; one is the mechanism to preserve the functional integrity of the contractile system and the other is the problem of the activity of contractile element itself. Moreover, the present author who has investigated on the tonic fiber and wants to distinguish it from the kinetic fiber in their function examines the behavior of the single cardiac muscle, assuming that the tonic and kinetic fiber in a skeletal muscle and the cardiac fiber may behave in a similar fashion.The main purpose of this report is to investigate that (1) whether only the ionic gradient across the plasma membrane contributes to the establishment of the resting potential or not, and (2) what factor determines the difference in the shape of action potential such as papillary type or Purkinje type.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• NODA KEN

  Department of Physiology, Kurume University School of Medicine

関連論文

• AN EXPERIMENTAL ASPECT OF THE HYPERPOLARIZATION OF S. J. P.
• THE EXPERIMENTS ON THE CARDIAC MUSCLE (2) THE EFFECT OF IONIC GRADIENT ACROSS MEMBRANE, ATP AND PYRUVIC ACID, ETC

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