Acute Myelopathy and Cerebellar Signs Associated with Uveitis with Positive Serum and Cerebrospinal Fluid Antibodies to HTLV-I.

スポンサーリンク

概要

• 論文の詳細を見る

• A 55-year-old man was admitted because of weakness in the legs of a few days duration. Neurological examination revealed paraparesis, ataxia of the left limbs, superficial hypoesthesia below the T-10 dermatome level and urinary retention. The antibody titers to human T-lymphotropic virus type I (HTLV-I) were ×640 in the serum and ×16 in the cerebrospinal fluid (CSF). The HTLV-I gag proteins, p19, p24, p46 and p53 were identified by Western blotting analysis of the serum and CSF. The CSF contained 691 white cells/c.mm; protein, 260 mg/dl; IgG, 84 mg/dl; and IgG index, 2.49 . Although the paraparesis and urinary retention disappeared within 10 days, he developed right uveitis which responded well to corticosteroid treatment . With improvement of the sensory impairment, cerebellar signs and CSF pleocytosis as well as uveitis, he was discharged eight weeks after admission. HTLV-I uveitis is a recently established disease entity. The case emphasizes the need to test blood and CSF for HTLV-I antibodies if patients developed myelopathy and cerebellar signs of acute onset, especially when associated with uveitis.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• HONDA EIICHIRO

  Department of Neurosurgery, Ohshima Hospital

関連論文

• Acute Myelopathy and Cerebellar Signs Associated with Uveitis with Positive Serum and Cerebrospinal Fluid Antibodies to HTLV-I.

スポンサーリンク