CLINICAL STUDIES ON BLOOD SUGAR REGULATION OF THE LIVER (PART 2):BLOOD SUGAR REGULATION OF THE LIVER TO ADRENALIN HYPERGLYCEMIA

概要

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Hyperglycemia which was induced by subcutaneous injection of adrenalin (0.01mg per kg) were observed on normal persons and patients of various hepatic and endocrine diseases. It was proved that on hepatic patients, especially with decompensate cirrhosis, the blood sugar elevation by adrenalin injection was lower and prolonged compared with that on control cases without hepatic damage. This fact was so charateristic as to permit the diagnosis of hepatic insufficiency, in which endocrine disturbances were excluded. Using hepatic venous catheterization, the increase of hepatic sugar output induced by adrenalin injection in all cases was found to precede arterial blood sugar elevation. And when glucose solution was previously injected intravenously this effect was in-tensified. The increase of hepatic sugar output on hepatic patients was smaller than that on normal persons. The blood sugar elevation in systemic artery were not always proportional with the grade of increase of hepatic sugar output.
社団法人日本内科学会の論文