高血圧症の腎機能に關する研究前編

概要

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In these studies, renal functions were estimated in 97 patients with hypertensive diseases (67 patients with essential hypertension and 30 patients with renal hypertension.) by clearance methods, and their values of blood pressure, retinal findings, proteinuria and electrocardiogram were compared with the data of renal clearance tests in these patients. As the results: 1) In the 67 patients with essential hypertension, reduction of RPF under the normal range was observed in about 3/5 of them, and decrease of GFR under the normal range was recognized in about 2/5 of them. It was found that the reduction of RPF in essential hypertension indicates the grade of renal hypofunctions most earliest and exactly. 2) In the patients of essential hypertension, it was found that systolic, diastolic and mean blood pressure indicate the correlation with RPF in statistically. 3) The correlation of RPF and GFR with the blood pressure in essential hypertension is contrary to that of renal hypertensions. (Fig. 28). 4) Between the degree of eyeground findings by Keith-Wageners classification and GFR, RBF and FF, there are some parallel correlations. 5) Particular attention was given to the correlation between RPF and proteinuria. The 80% cases of proteinuria showed the reduction of RPF. 6) The correlation between E.C.G. and GFR, RPF was not proved.
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