STUDIES ON THE MECHANISM OF REGULATION OF CORONARY CIRCULATION AND OF CORONARY DILATOR ACTION:I. SOME CONTRIBUTIONS TO THE MECHANISM OF REGULATION OF CORONARY CIRCULATION IN CORONARY SCLEROSIS
スポンサーリンク
概要
- 論文の詳細を見る
Coronary circulation and myocardial gaseous metabolism were studied on 25 patients by means of coronary sinus catheterization. These patients were classified into following three groups, according to the blood pressure and ECG. findings.: Group I; hypertension only (5 cases), Group II; hypertension with depressed ST·T (10 cases), Group III; coronary sclerosis without hypertension (10 cases).1) From the data previously reported concerning normal subjects and patients with hyperthyroidism and mild anemia, it was found that myocardial oxygen consumption were well correlated with cardiac work or with myocardial oxygen availability. As for coronary blood flow it was also found that it correlated fairly well with cardiac output or cardiac index.2) In groups I and II, coronary blood flow, myocardial oxygen consumption and its availability were increased, as compared with the normal value. These results were related to the increased cardiac work. In group II, coronary arterio-sinus oxygen difference and oxygen extraction ratio tended to increase, while these values were normal in group I.3) In group III, myocardial (xygen availability and oxygen consumption were slightly increased and coronary arterio-sinus oxygen difference and myocardial oxygen extraction ratio seemed to increase.4) Immediately after the exercise, coronary arterio-sinus oxygen difference and myocardial oxygen extraction ratio tended to increase in almost all cases in groups II and III, but in group I and normal subjects remained unaltered.From the data mentioned above, the author discussed on the increased coronary arterio-sinus oxygen difference and myocardial oxygen extraction ratio in coronary sclerosis, and concluded that they indicate the relatively diminished coronary blood flow and insufficiency of myocardial oxygenation.
- 社団法人 日本内科学会の論文
著者
関連論文
- STUDIES ON THE MECHANISM OF REGULATION OF CORONARY CIRCULATION AND OF CORONARY DILATOR ACTION:I. SOME CONTRIBUTIONS TO THE MECHANISM OF REGULATION OF CORONARY CIRCULATION IN CORONARY SCLEROSIS
- STUDIES ON THE MECHANISM OF REGULATION OF CORONARY CIRCULATION AND OF CORONARY DILATOR ACTION:II. EFFECTS OF CORONARY VASODILATOR DRUGS UPON THE CORONARY CIRCULATION AND MYOCARDIAL METABOLISM