ANTI-ANAPHYLACTIC ACTION OF CHLORPROMAZINE

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概要

• 論文の詳細を見る

• The effect of Chlorpromazine which is a blocking agent of autonomous nerves upon anaphylactic shock were experimentally studied and the following inhibitory actions of this drug were found.<BR>1. The administration of more than 1.0mg/kg of Chlorpromazine was able to protect guinea pigs from the death caused by passive anaphylactic shock.<BR>2. Chlorpromazine inhibited both prophylactically and symptomatically the passive and active local anaphylaxis of the intestine of guinea pigs and rabbits as observed with Magnus technique.<BR>3. Chlorpromazine prevented the Arthus reaction in rabbit skin.<BR>4. From the above results, the anti-anaphylactic actions of Chlorpromazine are considered to be effected both centrally and locally.

• The Keio Journal of Medicineの論文

著者

• NAKAYAMA Kiyoshi

  Department of Electrical & Electronics Engineering, College of Science & Technology, Sophia Universi

• NAKADATE KYUHEI

  Department of Legal Medicine, School of Medicine, Keio University

• KAMIKATAHIRA SHIGEAKI

  Department of Legal Medicine, School of Medicine, Keio University

• NAKAYAMA KIYOSHI

  Department of Legal Medicine, School of Medicine, Keio University

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• ANTI-ANAPHYLACTIC ACTION OF CHLORPROMAZINE

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