原発性肝癌細胞の異型度分類によるDNA合成の差異について

概要

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BrdU labeling indices of biopsy specimens from 16 HCC patients were examined, using an in vitro labeling technique.<BR>The labeling index (L.I.) of HCC was 7.06±2.71% (Mean±SE), ranging from 2.60% to 12.70%. There was a tendency that the more undifferentiated was the histological grade of Edmondson & Steiner's classification, the larger the L.I. of BrdU became; the mean L.I. in grade III group (10.64± 2.10%) was significancy (p>0.01) larger than that (5.87±1.61%) in Grade I-II group; i.e. the DNA synthesis was markedly increased in the undifferentiated HCC.
社団法人日本肝臓学会の論文