Measurement of equivalent lver volume(ELV) by Stoeckel's method.
スポンサーリンク
概要
- 論文の詳細を見る
Forty five patients with liver diseases received iv indocyanine green (3-4mg/kg). Blood samples were taken in 5 to 30 min interval in 90 to 120 min to determine serum ICG concentration (CP). Vm, Km, VP, b, h were calculated by Stceckel's methad and ELV was determined as a/b (a=Vm/Km). ELV was also determined directly by the computer, adding VL as the 6th parameter of the differential equations led from Stoeckel's model. Both ELV matched well to each other. The fitness of the model to serum ICG curve was excellent in 43 patients when judged by Akaike's Information Criterion. When h was less than 0.04, as it was in all patients studied, a simulatian program gave the calculated hepatic ICG concentrations which were equal to serum concentrations, only when ELV=a/b. The correlations between ELV and serum albumin, hepaplastin test, serum choline esterase, ICG R<SUB>15</SUB>, or hepatic glutathione S-transferase activities were statistically significant.
- 社団法人 日本肝臓学会の論文